Sequence : Envelope

Total row(s): 3
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Original Article
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In silico analysis of whole-genome sequences from India revealed the deletions of E protein. Patient data: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645280/table/tbl0005/?report=objectonly Of the 34 sequences with E gene deletions, 15 belonged to 19A, one belonged to 19B, 4 belonged to 20A and 20B each and remaining sequences could not be categorised into any of the clades defined by Nextstrain. C-terminal deletion in the E-gene of SARS-CoV-2 was loacated in different lineages and geographical locations (none of them had a travel history to COVID-19 infected countries)
33166565
(Virus Res)
PMID
33166565
Date of Publishing: 2021 Jan 2
Title Deletion in the C-terminal region of the envelope glycoprotein in some of the Indian SARS-CoV-2 genome
Author(s) nameKumar BK, Rohit A et al.
Journal Virus Res
Impact factor
2.6
Citation count: 6


Reporting multiple sequence analysis of Envelope protein (E) C-terminal domain sequence extracted from 13 genomes considered for study of SARS-CoV and SARS-CoV-2. 2 phylogenetic clades observed with the full genome is confirmed by SARS-CoV and SARS-CoV-2 E proteins.
32891874
(Microbes Infect)
PMID
32891874
Date of Publishing: 2020 Nov-Dec
Title Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis
Author(s) nameDe Maio F, Lo Cascio E et al.
Journal Microbes Infect
Impact factor
2.373
Citation count: 21
Date of Entry 2021 Aug 2


The mutation analysis of SARS-CoV-2 genomes from 13 different countries revealed the country-specific amino acid variations in the envelope protein. Variations in sequences were observed when 13 SARS-CoV-2 isolates were compared to SARS-CoV sequence: Table S1: (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470274/#pone.0238344.s001)
32881907
(PLoS One)
PMID
32881907
Date of Publishing: 2020
Title Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight
Author(s) nameKhan MI, Khan ZA et al.
Journal PLoS One
Impact factor
2.87
Citation count: 34



Molecular_interactions : Envelope

Total row(s): 2
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Original Article
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Reporting the predicted model of monomeric envelope protein structure of SARS-CoV and SARS-CoV-2 ~
32891874
(Microbes Infect)
PMID
32891874
Date of Publishing: 2020 Nov-Dec
Title Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis
Author(s) nameDe Maio F, Lo Cascio E et al.
Journal Microbes Infect
Impact factor
2.373
Citation count: 21
Date of Entry 2021 Aug 2


Reporting molecular binding and interaction of tight junction-associated PALS1 structure with Envelope protein C-terminal octapeptides of SARS-CoV and SARS-CoV-2 Key role of E protein C-terminal domain during infection is emphasized.
32891874
(Microbes Infect)
PMID
32891874
Date of Publishing: 2020 Nov-Dec
Title Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis
Author(s) nameDe Maio F, Lo Cascio E et al.
Journal Microbes Infect
Impact factor
2.373
Citation count: 21
Date of Entry 2021 Aug 2



Immunology : Envelope

Total row(s): 7
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Original Article
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Out of the many B-cell 'epitopes', SRVKNL ('envelope protein') could be a possible vaccine candidate as it enables direct interactions with immune receptor. Sequences of the SARS-CoV-2. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686850/bin/7079356.f1.txt
33299503
(Can J Infect Dis Med Microbiol)
PMID
33299503
Date of Publishing: 2020
Title An Immunoinformatics Study to Predict Epitopes in the Envelope Protein of SARS-CoV-2
Author(s) name Jakhar R, Gakhar SK.
Journal Can J Infect Dis Med Microbiol
Impact factor
1.41
Citation count: 4


These epitopes are highly antigenic, nontoxic ,and nonallergic in nature. Out of all, FLAFVVFLL and VLLFLAFVV epitopes were highly recommended as a candidate for the therapeutic peptide vaccine.
33299503
(Can J Infect Dis Med Microbiol)
PMID
33299503
Date of Publishing: 2020
Title An Immunoinformatics Study to Predict Epitopes in the Envelope Protein of SARS-CoV-2
Author(s) name Jakhar R, Gakhar SK.
Journal Can J Infect Dis Med Microbiol
Impact factor
1.41
Citation count: 4


All epitopes are antigenic and non-allergic and can induce IFN-.
33299503
(Can J Infect Dis Med Microbiol)
PMID
33299503
Date of Publishing: 2020
Title An Immunoinformatics Study to Predict Epitopes in the Envelope Protein of SARS-CoV-2
Author(s) name Jakhar R, Gakhar SK.
Journal Can J Infect Dis Med Microbiol
Impact factor
1.41
Citation count: 4


34 cytotoxic T cell epitopes located in spike glycoprotein, envelope protein, membrane protein, and nucleocapsid phosphoprotein were identified.
33257716
(Sci Rep)
PMID
33257716
Date of Publishing: 2020 Nov 30
Title Immunoinformatic design of a COVID-19 subunit vaccine using entire structural immunogenic epitopes of SARS-CoV-2
Author(s) nameBehmard E, Soleymani B et al.
Journal Sci Rep
Impact factor
4.12
Citation count: 15


14 helper T cell epitopes located in spike glycoprotein, envelope protein, and nucleocapsid phosphoprotein were identified.
33257716
(Sci Rep)
PMID
33257716
Date of Publishing: 2020 Nov 30
Title Immunoinformatic design of a COVID-19 subunit vaccine using entire structural immunogenic epitopes of SARS-CoV-2
Author(s) nameBehmard E, Soleymani B et al.
Journal Sci Rep
Impact factor
4.12
Citation count: 15


Eight (conserved) epitopes from envelop protein of SARS-CoV-2 were identified by in silico method.
32446902
(Microbes Infect)
PMID
32446902
Date of Publishing: 2020 May-Jun
Title Immunoinformatic analysis of the SARS-CoV-2 envelope protein as a strategy to assess cross-protection against COVID-19
Author(s) nameTilocca B, Soggiu A et al.
Journal Microbes Infect
Impact factor
2.373
Citation count: 25


Some of the immunogenic domains' conserved structure and mapping position were identified. Prediction of the B-cell epitopes failed to predict epitopes sequence.
32446902
(Microbes Infect)
PMID
32446902
Date of Publishing: 2020 May-Jun
Title Immunoinformatic analysis of the SARS-CoV-2 envelope protein as a strategy to assess cross-protection against COVID-19
Author(s) nameTilocca B, Soggiu A et al.
Journal Microbes Infect
Impact factor
2.373
Citation count: 25