Amino Acids


Last updated: 2021 Jul 28
Total hit(s): 9
Select item(s)
Key Findings
Comments
(You can add your comments too!)
Original Article
(hover to see details)
Amino acid alignment of the S gene in SARS-CoV-2 and coronaviruses found in bat and pangolin. NONE
33542420
(Sci Rep)
PMID
33542420
Date of Publishing: 2021 Feb 4
Title Dynamics of binding ability prediction between spike protein and human ACE2 reveals the adaptive strategy of SARS-CoV-2 in humans
Author(s) nameXue X, Shi J et al.
Journal Sci Rep
Impact factor
4.12
Citation count: 1
Date of Entry 2021 Jul 28


Phylogenetic trees were also reconstructed based on the sequences of S genes Phylogenetic analysis of SARS-CoV-2 suggests that SARS-CoV-2 is probably originated from a recombination event on the spike protein between a bat coronavirus and a pangolin coronavirus that endows it humans infectivity.
33542420
(Sci Rep)
PMID
33542420
Date of Publishing: 2021 Feb 4
Title Dynamics of binding ability prediction between spike protein and human ACE2 reveals the adaptive strategy of SARS-CoV-2 in humans
Author(s) nameXue X, Shi J et al.
Journal Sci Rep
Impact factor
4.12
Citation count: 1
Date of Entry 2021 Jul 28


Phylogenetic analysis of SARS-CoV-2 Spike glycoprotein protein (accession number: QIC53213.1), with ten other spike glycoprotein sequences from all the selected organisms. Spike glycoprotein of SARSCoV2 contains more antigenic peptides than that of the SARSCoV and MERS
32383269
(J Med Virol)
PMID
32383269
Date of Publishing: 2020 Oct
Title In silico studies on the comparative characterization of the interactions of SARSCoV2 spike glycoprotein with ACE2 receptor homologs and human TLRs
Author(s) name Choudhury A, Mukherjee S.
Journal J Med Virol
Impact factor
2.07
Citation count: 32


Phylogenetic analysis of human ACE2 receptor (accession number: AAT45083.1), with ACE2 receptor protein sequences from other genera of the animal kingdom. Though human and gorilla are closely related mammals , their clade is supported by a low BV (50%), it is inferred that the receptor protein in human could have followed a different ancestor than that of the gorilla.
32383269
(J Med Virol)
PMID
32383269
Date of Publishing: 2020 Oct
Title In silico studies on the comparative characterization of the interactions of SARSCoV2 spike glycoprotein with ACE2 receptor homologs and human TLRs
Author(s) name Choudhury A, Mukherjee S.
Journal J Med Virol
Impact factor
2.07
Citation count: 32


Phylogenetic and molecular evolutionary analyses of 42 mammal ACE2 protein sequences from wild animal protection lists of Hubei Province and Jiangxi Province, including human ACE2 protein No correlation between genetic distance and the interaction of ACE2/S was found.
32201080
(Biochem Biophys Res Commun)
PMID
32201080
Date of Publishing: 2020 May 21
Title Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection
Author(s) nameLuan J, Lu Y et al.
Journal Biochem Biophys Res Commun
Impact factor
2.73
Citation count: 80


Phylogenetic analysis of the S protein sequences SARS-CoV utilizes its S1 CTD,( RBD), to recognize the ACE2 receptor, it is hypothesised whether the CTD in SARS-CoV-2 is also the key region for interaction with its receptor hACE2.
32275855
(Cell)
PMID
32275855
Date of Publishing: 2020 May 14
Title Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
Author(s) nameWang Q, Zhang Y et al.
Journal Cell
Impact factor
27.35
Citation count: 447


Phylogenetic analysis of the C-terminal region
32275855
(Cell)
PMID
32275855
Date of Publishing: 2020 May 14
Title Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
Author(s) nameWang Q, Zhang Y et al.
Journal Cell
Impact factor
27.35
Citation count: 447


Phylogenetic analysis of the spike protein sequences of SARS-CoV-2, Bat-CoVs, and SARS-CoV, exposing relation between Bat-CoV with SARS-CoV-2 Sequence aligment for the RBD of spike protein of SARS-CoV-2 (MN938384), Bat-CoV (MN996532 and MG772933) and SARS-CoV (NC004718) revealed several amino acid substitutions and deletions in the RBD of Bat-CoV from Rhinolophus sinicus and Rhinolophus affinis compared to SARS-CoV-2, though they were closely related to SARS-CoV-2
32210742
(EXCLI J)
PMID
32210742
Date of Publishing: 2020
Title Role of changes in SARS-CoV-2 spike protein in the interaction with the human ACE2 receptor: An in silico analysis
Author(s) nameOrtega JT, Serrano ML et al.
Journal EXCLI J
Impact factor
2.01
Citation count: 72


The Phylogenetic analysis of the Replicase polyprotein (ORF 1ab) of 13 SARS-CoV-2 isolates from 13 different locations along with SARS-CoV sequences revealed that all 13 SARS-CoV-2 sequences clustered together in a single clade compared to SARS-CoV.
32881907
(PLoS One)
PMID
32881907
Date of Publishing: 2020
Title Comparative genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight
Author(s) nameKhan MI, Khan ZA et al.
Journal PLoS One
Impact factor
2.87
Citation count: 7