Metagenomic Next-Generation Sequencing

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An alternative method for the detection of SARS-CoV-2 directly from clinical specimens by application of direct Oxford Nanopore long-read third-generation metatranscriptomic and metagenomic sequencing technology. mNGS provided valuable information about the patients' respiratory microbiome and its relationship to coinfections. No SARS-CoV-2 reads were aligned to any of the ten samples that were suspected of having SARS-CoV-2 infection but were negative by RT-PCR
Date of Publishing: 2020 Nov 20
Title Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients
Author(s) nameMostafa HH, Fissel JA et al.
Journal mBio
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Citation count: 2