| || Reporting an amplification-free, fluorescence-based diagnostic method, namely Hybrid Capture Fluorescence Immunoassay (HC-FIA), for diagnosing SARS-CoV-2. It is carried on a lateral flow strip and targets ORF1ab, E, and the N regions of the genome to detect SARS-CoV-2. The assay resulted in 100% and 99% sensitivities and specificities, respectively. ||This assay is based on the capture of RNA-DNA hybrids and on immunofluorescence analysis.
The SARS-CoV-2 HC-FIA detection system Fig.1 (https://www.nature.com/articles/s41551-020-00655-z#Fig1) ✍ || 33273714 |
(Nat Biomed Eng)
Date of Publishing: 2020 Dec
|Title ||Rapid lateral flow immunoassay for the fluorescence detection of SARS-CoV-2 RNA|
|Author(s) name||Wang D, He S et al.|
|Journal ||Nat Biomed Eng|
|Citation count ||3|