Auto Summaries - Immunology
Last updated: 2022 Jan 4
Total hit(s): 11222
COVID-19 booster vaccine willingness
Danes are a population with a high acceptance of the initial round of COVID-19 vaccination. 90% indicated that they were willing to receive the booster vaccine, if/once offered. The only characteristic associated with booster vaccine willingness at the set level of statistical significance (0.05) was age.
Dan Med J
2022 Dec 7
The significant immune escape of pseudotyped SARS-CoV-2 variant Omicron
The emergence of Omicron/BA.1 has brought new challenges to fight against SARS-CoV-2. A large number of mutations in the Spike protein suggest that its susceptibility to immune protection elicited by the existing COVID-19 infection and vaccines may be altered.
Emerg Microbes Infect
2022 Dec
Hesitancy towards Covid-19 vaccination among the healthcare workers in Iraqi Kurdistan
An anonymous questionnaire on the willingness of receiving Covid-19 vaccination was submitted to a sample of HWCs in the Dohuk Governorate, Iraqi Kurdistan Region. Overall, 1704 questionnaires were analysed by means of univariate and multivariate statistics. The study included 978 males and 726 females (Mean age: 36.910.1), working in Primary Health Centres (65.8%) or in Public Hospitals (34.2%) Professions ranged from being physician/paramedics (39.3%) to administrative/laboratory staff (31.7%) Midwifes (61.1%) and assistant nurses (45.5%) were the most hesitant.
Public Health Pract (Oxf)
2022 Jun
Effectiveness of message framing in changing COVID-19 vaccination intentions: Moderating role of travel desire
Findings show the importance of travel desire along with message framing and message appeal on changing individuals' COVID-19 vaccination intentions in public health communications. Travel desire is found to moderate the effect of vaccine risk perception on vaccination intentions. Loss-framed messages are more effective than emotional-rational messages in reducing risk perceptions.
Tour Manag
2022 Jun
SARS-CoV-2 involvement in central nervous system tissue damage
SARS-CoV-2 virus infects multiple organs including the brain. Patients with COVID-19 infection experience an array of neurological signs ranging in severity from headaches to life-threatening strokes. This overview attempts to give a thorough insight into SARS coronavirus neurological infection and highlights the possible mechanisms leading to the neurological manifestations observed in infected patients.
Neural Regen Res
2022 Jun
Acute asthma exacerbation after SARS-CoV-2 vaccine (SinovacĀ®): a case report
A 76-year-old female received a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine (CoronaVac, Sinovac() and subsequently experienced chest discomfort. She was hospitalized with a preliminary diagnosis of drug-induced pneumonitis and acute asthma exacerbation. During her hospitalization, 40 mg/d systemic steroid, 4 times a day salbutamol nebulized, 2 L/min inhaled oxygen therapy and 400mg/d moxifloxacin intravenous were administered for 5 days. One month later, the thorax computed tomography scan revealed that the previous findings were almost completely regressed.
Med Gas Res
2022 Apr-Jun
Toward controlling of a pandemic: How self-control ability influences willingness to take the COVID-19 vaccine
Self-control is often associated with adherence to social norms and with engagement in socially desirable behaviors. Study found non-student adults with higher self-control strength levels were more likely to accept vaccine appointments. Study 3 found participants exerting a high level of effort for attentional self control in the incongruent Stroop task condition showed lower COVID-19 vaccine acceptance than participants in the congruent condition.
Pers Individ Dif
2022 Apr
Global metabolome profiling of COVID-19 respiratory specimen using high-resolution mass spectrometry (HRMS)
This protocol provides step-by-step instructions on sample collection from patients, followed by metabolite extraction. We use ultra-high-pressure liquid chromatography (UHPLC) coupled with high-resolution mass spectrometry (HRMS) for data acquisition and describe the steps for data analysis. The protocol was standardized with specific customization for SARS-CoV-2-containing respiratory specimens.
STAR Protoc
2022 Mar 18
Clinical data to be used as a foundation to combat Covid-19 vaccine hesitancy
The facts, myths, and conspiracy theories centered on the Covid-19 pandemic have dominated social media accounts, local and national newspapers, as well as television programs. Strategies need to be evolved to counter vaccine hesitancy and mitigate health disparities in at-risk populations.
J Interprof Educ Pract
2022 Mar
A case report of new onset graves' disease induced by SARS-CoV-2 infection or vaccine?
The relationship that possibly exists between the COVID-19 infection, the newly developed vaccines, and thyroid disease are still under investigation. We are reporting the first case of new-onset graves' disease in a young, healthy man after being infected with the virus. It can cause systemic inflammation, which can lead to multiorgan involvement and subsequent damage.
J Clin Transl Endocrinol Case Rep
2022 Mar
Vaccine efficacy and SARS-CoV-2 control in California and U.S. during the session 2020-2026: A modeling study
A mathematical model study has been done on the importance of vaccination and vaccine efficiency rate during an ongoing pandemic. The more effective a vaccine is, the less people suffer from this malign infection. According to this study, the unconfirmed-infectious and infected cases will be under control at the end of 2027 and at the mid of 2028, respectively.
Infect Dis Model
2022 Mar
Cant find
Strategies to minimize inequity in COVID-19 vaccine access in the US: Implications for future vaccine rollouts
College of Pharmacy, University of Utah, Salt Lake City, Utah, U.S., is a college of pharmacy science. The author has published more than 1,000 books on pharmacology and other topics. Her book will be published at the University's Pharmacy Library.
Lancet Reg Health Am
2022 Mar
On the dynamical model for COVID-19 with vaccination and time-delay effects: A model analysis supported by Yangzhou epidemic in 2021
2019 novel coronavirus (COVID-19) emerged at the end of 2019 has a great influence on the health and lives of people all over the world. The spread principle is still unclear. This paper considers a novel evolution model in terms of an integral-differential equation.
Appl Math Lett
2022 Mar
COVID-19 vaccine hesitancy: The effects of combining direct and indirect online opinion cues on psychological reactance to health campaigns
" Study aims to examine whether and how user-generated comments and reaction emojis on COVID-19 vaccine-promoting Facebook posts induce psychological reactance to posts and vaccine hesitancy in audiences of the posts. Pro-vaccine comments triggered less reactance than anti-vaccines comments when the pro-vignant comments were accompanied by agreement emojas (i.e., ""like"" and ""love) The study included 465 U.S. adults including 465 American adults."
Comput Human Behav
2022 Feb
Aseptic meningitis after BNT-162b2 COVID-19 vaccination
Vaccination widely regarded as the most important strategy to contain the pandemic. Concern has emerged due to sporadic reports of immune-mediated adverse effects. As of August 19, 2021, 4.54 million individuals had received COVID-19 vaccines in Singapore. We report a case series of two patients who developed aseptic meningitis after vaccination.
Brain Behav Immun Health
2022 Feb
A novel ensemble fuzzy classification model in SARS-CoV-2 B-cell epitope identification for development of protein-based vaccine
B-cell epitope identification with the aid of an accurate prediction method is one of the most important steps in epitope-based vaccine development, immunodiagnostic testing, antibody production, disease diagnosis, and treatment. We hope that the developed epitope prediction method will help design effective vaccines and drugs against future outbreaks of the coronavirus family, especially SARS-CoV-2 and its possible mutations.
Appl Soft Comput
2022 Feb
MicroRNAs based regulation of cytokine regulating immune expressed genes and their transcription factors in COVID-19
Coronavirus disease 2019 is characterized by the elevation of a broad spectrum of inflammatory mediators associated with poor disease outcomes. We aimed at an in-silico analysis of regulatory microRNA and their transcription factors for these inflammatory genes that may help to devise potential therapeutic strategies in the future.
Meta Gene
2022 Feb
Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate
SARS-CoV-2 protein subunit vaccines are currently being evaluated by multiple manufacturers to address the global vaccine equity gap, and need for low-cost, easy to scale, safe, and effective COVID-19 vaccines. In this paper, we report on the generation of the RBD203-N1 yeast expression construct, which produces a recombinant protein capable of eliciting a robust immune response and protection in mice against infections.
Protein Expr Purif
2022 Feb
Linking the behavioral immune system to COVID-19 vaccination intention: The mediating role of the need for cognitive closure and vaccine hesitancy
Study finds that perceived vulnerability to disease (PVD) is associated with vaccination intentions through the need for cognitive closure (NCC) and vaccine hesitancy. Perceived infectability, on the other hand, is directly related to vaccination intention. We discuss the potential benefits of considering the roles of BIS and NCC in campaigns and policies aimed at increasing COVID-19 vaccine uptake.
Pers Individ Dif
2022 Feb
The behavioral immune system and vaccination intentions during the coronavirus pandemic
The behavioral immune system is considered to be a psychological adaptation that decreases the risk of infection. Research suggests that, in the current environment, this system can produce attitudes with negative health consequences. Those with higher germ aversion during the pandemic perceived vaccines to be safer and had higher intentions to accept vaccination.
Pers Individ Dif
2022 Feb
Factors Influencing University Students' Acceptance to Undertake the COVID-19 Vaccine in Jordan
This article reports findings regarding factors that influence university students' decision of acceptability to the COVID-19 vaccine in Jordan. Results highlight the continued need for clear and consistent information about the vaccine by health care decision-makers and university administrations. The study was conducted at Al Balqa' Applied University, Salt, Jordan (Dr Al Hadid) and Clinical Department, Faculty of Nursing, Al-Zaytoonah University of Jordan, Amman, Jordan.
Crit Care Nurs Q
2022 Jan-Mar 01
[Pregnancy and vaccination COVID-19]
Clin Invest Ginecol Obstet
2022 Jan-Mar
Using Public Deliberation to Set Priorities: The Case of COVID-19 Vaccine Access in New York City
The New York City health department sought guidance from members of the public about the fairest approach to early-stage vaccine distribution. Participants focused on equity, recognizing that those at highest risk were largely low-income populations of color and individuals living in low-resourced neighborhoods. Recommendations for prioritization emphasized risk of severe morbidity and mortality, and work and neighborhood conditions with fewer protections (eg, in-person work, exposure to many people)
J Public Health Manag Pract
2022 Jan-Feb 01
SARS-CoV-2 spreads through cell-to-cell transmission
SARS-CoV-2 is a highly transmissible coronavirus responsible for the global COVID-19 pandemic. Cell-to-cell transmission refractory to inhibition by neutralizing antibody or convalescent sera of patients. Treatment of cocultured cells with endosomal entry inhibitors impairs cellular transmission.
Proc Natl Acad Sci U S A
2022 Jan 4
Trends in COVID-19 vaccination intent and factors associated with deliberation and reluctance among adult homeless shelter residents and staff, 1 November 2020 to 28 February 2021 - King County, Washington
Little is known about COVID-19 vaccination intent among people experiencing homelessness. Strong disparities in vaccine intent based on race, education, and prior vaccine history were observed. Increased vaccine intent over the study period was not detected. An intersectional, person-centered approach to addressing health inequities by public health authorities planning vaccination campaigns in shelters is recommended.
2022 Jan 3