Interacting Proteins

Viral protein-Other antibody complex

Last updated: 2021 Apr 19

Total row(s): 13

Macro molecule	Gene	Interacting molecule/ protein	Interacting gene	PDB ID	Title	Structure Title	Experimental Method	Resolution (Å)	PubMed ID	Structure
Spike glycoprotein	S, 2	Nanobody Ty1	~	6ZXN	An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.	Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing nanobodies (Ty1)	ELECTRON MICROSCOPY	2.93	32887876	3D view
Spike glycoprotein	S, 2	Neutralising sybody (Sb23)	~	7A29	Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.	Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation	ELECTRON MICROSCOPY	2.94	33149112	3D view
Spike glycoprotein	S, 2	Sybody 23	~	7A25	Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.	Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23)	ELECTRON MICROSCOPY	3.06	33149112	3D view
Spike glycoprotein	S, 2	Nanobody	~	6Z43	Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2	Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex	ELECTRON MICROSCOPY	3.3	To be published	3D view
Replicase polyprotein 1a	rep, 1a-1b	Ubiquitin-like protein ISG15	Isg15, G1p2, Ucrp,	6YVA	Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.	PLpro-C111S with mISG15	X-RAY DIFFRACTION	3.18	32726803	3D view
Spike glycoprotein	S, 2	Nanobody H11-D4	~	6YZ5	H11-D4 complex with SARS-CoV-2 RBD	H11-D4 complex with SARS-CoV-2 RBD	X-RAY DIFFRACTION	1.8	To be published	3D view
Spike glycoprotein,Fibritin	S,2, wac	Nanobody H11-H4	~	6ZHD	H11-H4 bound to Spike	H11-H4 bound to Spike	ELECTRON MICROSCOPY	3.7, 3.7	To be published	3D view
Spike glycoprotein	S,2	Synthetic nanobody SR4	~	7C8V	Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization	Structure of sybody SR4 in complex with the SARS-CoV-2 S Receptor Binding domain (RBD)	X-RAY DIFFRACTION	2.15	To be published	3D view
Spike glycoprotein	S,2	Synthetic nanobody MR17	~	7C8W	Rapid selection of synthetic nanobodies against the receptor binding domain of SARS-CoV-2 S protein	Structure of sybody MR17 in complex with the SARS-CoV-2 S receptor-binding domain (RBD)	X-RAY DIFFRACTION	2.77	To be published	3D view
Spike glycoprotein	S,2	sybody MR17-K99Y	~	7CAN	Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization	Structure of sybody MR17-K99Y in complex with the SARS-CoV-2 S Receptor-binding domain (RBD)	X-RAY DIFFRACTION	2.94	To be published	3D view
Spike glycoprotein	S,2	Nanobody Nb20	~	7JVB	Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2.	Crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD) with nanobody Nb20	X-RAY DIFFRACTION	3.287	33154108	3D view
Spike glycoprotein	S,2	Synthetic nanobody Nb6	~	7KKK	An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.	SARS-CoV-2 Spike in complex with neutralizing nanobody Nb6	ELECTRON MICROSCOPY	3.03	33154106	3D view
Spike glycoprotein	S,2	Synthetic nanobody mNb6	~	7KKL	An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.	SARS-CoV-2 Spike in complex with neutralizing nanobody mNb6	ELECTRON MICROSCOPY	2.85	33154106	3D view