| Replicase polyprotein 1a (A, C chains) |
rep, 1a-1b |
Replicase polyprotein 1a (B,D chains) |
rep, 1a-1b |
6YHU |
Structural analysis of the putative SARS-CoV-2 primase complex. |
Crystal structure of the nsp7-nsp8 complex of SARS-CoV-2 |
X-RAY DIFFRACTION |
2 |
32535228 |
3D view |
| nsp7 |
rep, 1a-1b |
nsp8 |
rep, 1a-1b |
6XIP |
The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 |
The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 |
X-RAY DIFFRACTION |
1.5 |
to be published |
3D view |
| NSP 8 |
rep, 1a-1b |
NSP 7 |
rep, 1a-1b |
6M5I |
Crystal structure of 2019-nCoV nsp7-nsp8c complex |
Crystal structure of 2019-nCoV nsp7-nsp8c complex |
X-RAY DIFFRACTION |
2.496 |
to be published |
3D view |
| NSP 12 ( A chain ) |
rep, 1a-1b |
NSP 7 (C chain)
NSP 8 (B, D chains) |
rep, 1a-1b |
6M71 |
Structure of the RNA-dependent RNA polymerase from COVID-19 virus. |
SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors |
ELECTRON MICROSCOPY |
2.9 |
32277040 |
3D view |
| Nsp16 |
rep, 1a-1b |
Nsp10 |
rep, 1a-1b |
7BQ7 |
Crystal structure of 2019-nCoV nsp16-nsp10 complex |
Crystal structure of 2019-nCoV nsp16-nsp10 complex |
X-RAY DIFFRACTION |
2.37 |
To be published |
3D view |
| Nsp16 |
rep, 1a-1b |
Nsp10 |
rep, 1a-1b |
7C2I |
Crystal structure of SARS-CoV-2 nsp10/nsp16 2'-O-methylase and its implication on antiviral drug design. |
Crystal structure of nsp16-nsp10 heterodimer from SARS-CoV-2 in complex with SAM (with additional SAM during crystallization) |
X-RAY DIFFRACTION |
2.5 |
32728018 |
3D view |
| RNA-directed RNA polymerase |
rep, 1a-1b |
Nsp 8
Nsp 7 |
rep, 1a-1b |
7C2K |
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. |
COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex |
ELECTRON MICROSCOPY |
2.93 |
32526208 |
3D view |
| Nsp12 |
rep, 1a-1b |
Nsp8
Nsp7 |
rep, 1a-1b |
7BV1 |
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. |
Cryo-EM structure of the apo nsp12-nsp7-nsp8 complex |
ELECTRON MICROSCOPY |
2.8 |
32358203 |
3D view |
| Replicase polyprotein 1ab ( A, B, D ) |
rep, 1a-1b |
Replicase polyprotein 1ab C |
rep, 1a-1b |
7BW4 |
Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2. |
Structure of the RNA-dependent RNA polymerase from SARS-CoV-2 |
ELECTRON MICROSCOPY |
3.7 |
32531208 |
3D view |
| Nsp7 |
rep, 1a-1b |
Nsp8 |
rep, 1a-1b |
7JLT |
Crystal Structure of SARS-CoV-2 NSP7-NSP8 complex. |
Crystal Structure of SARS-CoV-2 NSP7-NSP8 complex. |
X-RAY DIFFRACTION |
2.7 |
To be published |
3D view |
| Nsp16 |
rep, 1a-1b |
Nsp10 |
rep, 1a-1b |
6W4H |
1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex from SARS-CoV-2 |
1.80 Angstrom Resolution Crystal Structure of NSP16 - NSP10 Complex from SARS-CoV-2 |
X-RAY DIFFRACTION |
1.8 |
To be published |
3D view |
| 2'-O-methyltransferase |
rep, 1a-1b |
Nsp10 |
rep, 1a-1b |
6W61 |
Crystal Structure of the methyltransferase-stimulatory factor complex of NSP16 and NSP10 from SARS CoV-2. |
Crystal Structure of the methyltransferase-stimulatory factor complex of NSP16 and NSP10 from SARS CoV-2. |
X-RAY DIFFRACTION |
2 |
To be published |
3D view |
| Nsp16 |
rep, 1a-1b |
Nsp10 |
rep, 1a-1b |
6W75 |
1.95 Angstrom Resolution Crystal Structure of NSP10 - NSP16 Complex from SARS-CoV-2 |
1.95 Angstrom Resolution Crystal Structure of NSP10 - NSP16 Complex from SARS-CoV-2 |
X-RAY DIFFRACTION |
1.951 |
To be published |
3D view |
| Nsp7 |
rep, 1a-1b |
Nsp8 |
rep, 1a-1b |
6WIQ |
Crystal structure of the co-factor complex of NSP7 and the C-terminal domain of NSP8 from SARS CoV-2 |
Crystal structure of the co-factor complex of NSP7 and the C-terminal domain of NSP8 from SARS CoV-2 |
X-RAY DIFFRACTION |
2.85 |
To be published |
3D view |
| Nsp16 |
rep, 1a-1b |
Nsp10 |
rep, 1a-1b |
6WKQ |
1.98 Angstrom Resolution Crystal Structure of NSP16-NSP10 Heterodimer from SARS-CoV-2 in Complex with Sinefungin. |
1.98 Angstrom Resolution Crystal Structure of NSP16-NSP10 Heterodimer from SARS-CoV-2 in Complex with Sinefungin |
X-RAY DIFFRACTION |
1.98 |
To be published |
3D view |
| Nsp7 |
rep, 1a-1b |
Nsp8 |
rep, 1a-1b |
6WQD |
The 1.95 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 |
The 1.95 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS-CoV-2 |
X-RAY DIFFRACTION |
1.95 |
To be published |
3D view |
| Nsp7 |
rep, 1a-1b |
Nsp8 |
rep, 1a-1b |
6WTC |
Crystal Structure of the Second Form of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 |
Crystal Structure of the Second Form of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 |
X-RAY DIFFRACTION |
1.85 |
To be published |
3D view |