Viral protein


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Key Findings
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV05-163 and CR3022
PMID
Title https://doi.org/10.1101/2021.02.16.430500
Author(s) name-
Journal
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Citation count
Date of publishing-
This structure based on SARS-CoV-2 spike receptor binding domain (RBD) using computational methods predicts antibody RBD recognition signatures which can be used to design vaccine against Covid-19.
PMID
Title Structural and energetic profiling of SARS-CoV-2 antibody recognition and the impact of circulating variants
Author(s) name-
Journal
Impact factor
Citation count
Date of publishing-
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 2)
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to VH ab8
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to VH ab8 (focused refinement of RBD and VH ab8)
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (focused refinement of RBD and Fab ab1)
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 1)
PMID 33914735
Title Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
Author(s) nameZhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S.
Journal PLoS Biol
Impact factor7.62
Citation count
Date of publishing2021 Apr 29
Structural characterisation of SARSCoV- 2 RBD and bACE2-Rm complex. (Rm - Rhinolophus macrotis)
PMID 33335073
Title Cross-species recognition of SARS-CoV-2 to bat ACE2
Author(s) nameLiu K, Tan S, Niu S, Wang J, Wu L, Sun H, Zhang Y, Pan X, Qu X, Du P, Meng Y, Jia Y, Chen Q, Deng C, Yan J, Wang HW, Wang Q, Qi J, Gao GF.
Journal Proc Natl Acad Sci U S A
Impact factor9.35
Citation count1
Date of publishing2021 Jan 5
Structural characterization of S-2H2-F1 with one RBD in up configuration and two RBDs in down configuration, where only RBD in up configuration is bound to 2H2 Fab
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of S-2H2-F3a with two RBDs in up configuration and one RBD in down configuration, where each RBD is bound to 2H2 Fab.
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of S-3C1-F3b with all the three RBDs in up configuration and each of them bound to 3C1 Fab
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of S-2H2-F2 with two RBDs in up configuration and one RBD in down configuration, where each of the RBD in up configuration is bound to 2H2 Fab.
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of S-2H2-F3b with three RBDs in up configuration and each RBD is bound to 2H2 Fab.
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of SARS-CoV-2 S protein in open state
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of SARS-CoV-2 S protein in closed state
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of S-3C1-F1 with one RBD in up configuration and two RBDs in down configuration, where the up configuration RBD is bound to 3C1 fab
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of S-3C1-F2 with two RBDs in up configuration and one RBD in down configuration, where the two up configuration RBD is bound to 3C1 fab.
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of S-3C1-F3a with two RBDs in up configuration and one RBD in down configuration, where each RBD is bound to 3C1 fab.
PMID 33431876
Title Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
Author(s) nameZhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z.
Journal Nat Commun
Impact factor11.8
Citation count1
Date of publishing2021 Jan 11
Structural characterization of SARS-CoV-2 3Q-2P full-length dimers of spike trimers of the leading subunit vaccine candidate (NVAX-CoV2373) from Novavax.
PMID 33082295
Title Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate
Author(s) nameBangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR 3rd, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB.
Journal Science
Impact factor20.57
Citation count12
Date of publishing2020 Nov 27
Structural characterization of SARS-CoV-2 3Q-2P full-length prefusion spike trimer (C3 symmetry) of the leading subunit vaccine candidate (NVAX-CoV2373) from Novavax.
PMID 33082295
Title Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate
Author(s) nameBangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR 3rd, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB.
Journal Science
Impact factor20.57
Citation count12
Date of publishing2020 Nov 27
Structural characterisation of SARS-CoV-2 mini replication and transcription complex
PMID 33208736
Title Architecture of a SARS-CoV-2 mini replication and transcription complex
Author(s) nameYan L, Zhang Y, Ge J, Zheng L, Gao Y, Wang T, Jia Z, Wang H, Huang Y, Li M, Wang Q, Rao Z, Lou Z.
Journal Nat Commun
Impact factor11.8
Citation count4
Date of publishing2020 Nov 18
Structural characterisation of SARS-CoV-2 mini replication and transcription complex
PMID 33208736
Title Architecture of a SARS-CoV-2 mini replication and transcription complex
Author(s) nameYan L, Zhang Y, Ge J, Zheng L, Gao Y, Wang T, Jia Z, Wang H, Huang Y, Li M, Wang Q, Rao Z, Lou Z.
Journal Nat Commun
Impact factor11.8
Citation count4
Date of publishing2020 Nov 18