Viral shedding


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Key Findings
The virus titers in the tracheal and lung tissues of infected Hamsters showed higher virus replication in the lung tissues of hamsters infected with WT SARS-CoV-2 than Del-mut-1 variant infected hamsters.
PMID 32301390
Title Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction
Author(s) nameLau SY, Wang P, Mok BW, Zhang AJ, Chu H, Lee AC, Deng S, Chen P, Chan KH, Song W, Chen Z, To KK, Chan JF, Yuen KY, Chen H.
Journal Emerg Microbes Infect
Impact factor5.84
Citation count36
Date of publishing2020 Dec
Hamsters infected with mutant SARS-CoV-2 (G614 virus) showed higher viral load in the nasal washes and the tracheae, but not in the lungs, than those of Hamsters infected with WT SARS-CoV-2 (D614 virus).
PMID 33106671
Title Spike mutation D614G alters SARS-CoV-2 fitness
Author(s) namePlante JA, Liu Y, Liu J, Xia H, Johnson BA, Lokugamage KG, Zhang X, Muruato AE, Zou J, Fontes-Garfias CR, Mirchandani D, Scharton D, Bilello JP, Ku Z, An Z, Kalveram B, Freiberg AN, Menachery VD, Xie X, Plante KS, Weaver SC, Shi PY.
Journal Nature
Impact factor24.36
Citation count38
Date of publishing2020 Oct 26
12-24 months old male and female ferrets inoculated with SARS-CoV-2 virus had highest viral RNA in nasal washes. Viral RNA was also detected in saliva specimens.
PMID 32259477
Title Infection and Rapid Transmission of SARS-CoV-2 in Ferrets
Author(s) nameKim YI, Kim SG, Kim SM, Kim EH, Park SJ, Yu KM, Chang JH, Kim EJ, Lee S, Casel MAB, Um J, Song MS, Jeong HW, Lai VD, Kim Y, Chin BS, Park JS, Chung KH, Foo SS, Poo H, Mo IP, Lee OJ, Webby RJ, Jung JU, Choi YK.
Journal Cell Host Microbe
Impact factor10.45
Citation count181
Date of publishing2020 May 13
12-24 months old male and female ferrets infected through direct contact with infected ferrets had viral RNA in nasal washes, saliva, fecal and urine samples.
PMID 32259477
Title Infection and Rapid Transmission of SARS-CoV-2 in Ferrets
Author(s) nameKim YI, Kim SG, Kim SM, Kim EH, Park SJ, Yu KM, Chang JH, Kim EJ, Lee S, Casel MAB, Um J, Song MS, Jeong HW, Lai VD, Kim Y, Chin BS, Park JS, Chung KH, Foo SS, Poo H, Mo IP, Lee OJ, Webby RJ, Jung JU, Choi YK.
Journal Cell Host Microbe
Impact factor10.45
Citation count181
Date of publishing2020 May 13
2 out of 6 12-24 months old male and female ferrets in indirect contact with infected ferrets had viral RNA in nasal washes and fecal specimens.
PMID 32259477
Title Infection and Rapid Transmission of SARS-CoV-2 in Ferrets
Author(s) nameKim YI, Kim SG, Kim SM, Kim EH, Park SJ, Yu KM, Chang JH, Kim EJ, Lee S, Casel MAB, Um J, Song MS, Jeong HW, Lai VD, Kim Y, Chin BS, Park JS, Chung KH, Foo SS, Poo H, Mo IP, Lee OJ, Webby RJ, Jung JU, Choi YK.
Journal Cell Host Microbe
Impact factor10.45
Citation count181
Date of publishing2020 May 13