Epidemiology


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Key Findings
In 19205 participants, the seroprevalence was <3% until Mid-December 2020 in all regions. Mostly low seroprevalence was estimated in Reutlingen, Aachen, Freiburg, and OsnabrŁck after the first wave while serological study in Magdeburg cumulatively already indicates the onset of the second wave.
PMID
Title SARS-CoV-2 seroprevalence in Germany - a population based sequential study in five regions
Author(s) nameManuela Harries
Journal
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Date of publishing2021 May 6
Serological survey of mild/asymptomatic SARS-CoV-2 infected individuals were tested with three immunoassays. Antibodies were found to be present for atleast 8 months after infection.
PMID
Title Persistence and detection of anti-SARS-CoV-2 antibodies: immunoassay heterogeneity and implications for serosurveillance
Author(s) name-
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Serological survey of mild/asymptomatic SARS-CoV-2 infected individuals were tested with three immunoassays. Antibodies were found to be present for atleast 8 months after infection.
PMID
Title Serological survey of mild/asymptomatic SARS-CoV-2 infected individuals were tested with three immunoassays. Antibodies were found to be present for atleast 8 months after infection.
Author(s) name-
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This study focused on two genes ACE2 and TMPRSS2, the variations of which relates to COVID 19 infection and disease progression. SNPs with higher allele frequencies for ACE2 and TMPRSS2 were found in African and East Asian population than Europeans and Americans which could explain the differential susceptibility to the infection.
PMID
Title COVID-19: Variant screening, an important step towards precision epidemiology
Author(s) name-
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160 whole-genome sequences were obtained from all provinces in Ecuador. Global B.1.1.74 lineage was the predominant lineage (39.4%) in early phase in Ecuador. Transmission lineages D and H were the dominant lineages in the data set in all provinces.
PMID
Title Genomic epidemiology of SARS-CoV-2 transmission lineages in Ecuador.
Author(s) name-
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Airborne/Aerosol transmission of SARS-CoV-2 is the highly prevalent route when compared to others, suggested by 10 concrete and consistent studies.
PMID 33865497
Title Ten Scientific reasons in support of airborne transmission of SARS-CoV-2
Author(s) nameGreenhalgh T, Jimenez JL, Prather KA, Tufekci Z, Fisman D, Schooley R.
Journal Lancet
Impact factor43.38
Citation count
Date of publishing2021 May 1
Transmission of SARS-CoV-2 has been shown to occur via ocular surfaces of the eyes, demonstrated by presence of viral RNA in the conjunctival sac, which could gain entry into lungs through the respiratory tract. Effective measures such as protective eye equipment and hand hygiene could be used to prevent ocular transmission in healthcare workers.
PMID 33986784
Title COVID-19: risk of ocular transmission in health care professionals
Author(s) nameMatos AG, Sarquis IC, Santos AAN, Cabral LP.
Journal Rev Bras Med Trab
Impact factor
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Date of publishing2021 Apr 30
SARS-CoV-2 transmission dynamics showed that central nodes of each cluster were located at either end of the Amazonas city, suggesting two independent introduction of the virus and tranmission events but with slight overlapping of both clusters.
PMID 33857136
Title Deciphering the introduction and transmission of SARS-CoV-2 in the Colombian Amazon Basin
Author(s) nameBallesteros N, Mu√Īoz M, Pati√Īo LH, Hern√°ndez C, Gonz√°lez-Casabianca F, Carroll I, Santos-Vega M, Cascante J, Angel A, Feged-Rivadeneira A, Palma-Cuero M, Fl√≥rez C, Gomez S, van de Guchte A, Khan Z, Dutta J, Obla A, Alshammary HA, Gonzalez-Reiche AS, Hernandez MM, Sordillo EM, Simon V, van Bakel H, Paniz-Mondolfi AE, Ram√≠rez JD.
Journal PLoS Negl Trop Dis
Impact factor4.4
Citation count
Date of publishing2021 Apr
Transmissibility of novel SARS-CoV-2 variant (VOC 202012/01) was higher due to a higher viral load in samples, which led to increased incidence of cases owing to its higher reproduction number (43-90%) when compared to the preexisting variants.
PMID 33658326
Title Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England
Author(s) nameDavies NG, Abbott S, Barnard RC, Jarvis CI, Kucharski AJ, Munday JD, Pearson CAB, Russell TW, Tully DC, Washburne AD, Wenseleers T, Gimma A, Waites W, Wong KLM, van Zandvoort K, Silverman JD; CMMID COVID-19 Working Group; COVID-19 Genomics UK (COG-UK) Consortium, Diaz-Ordaz K, Keogh R, Eggo RM, Funk S, Jit M, Atkins KE, Edmunds WJ.
Journal Science
Impact factor20.57
Citation count1
Date of publishing2021 Mar 3
SARS-CoV-2 transmission could be reduced by considering significant factors such as airflow rate, exposure time and proximity to the infected person.The study also identified the relationship between factors such as physical environment, activity, time and the exposure to viral aerosols.
PMID 33495667
Title Modelling uncertainty in the relative risk of exposure to the SARS-CoV-2 virus by airborne aerosol transmission in well mixed indoor air
Author(s) nameJones B, Sharpe P, Iddon C, Hathway EA, Noakes CJ, Fitzgerald S.
Journal Build Environ
Impact factor5.2
Citation count1
Date of publishing2021 Mar 15
Higher risk of contracting SARS-CoV-2 infection was reported in individuals with B+ blood type (36.3%) than those with O+ blood type (29%) and A+ blood type (20.9%). Post-COVID complications such as sleep disturbances, pains, anxiety and depression were also reported.
PMID 33520252
Title A multi-centre, cross-sectional study on coronavirus disease 2019 in Bangladesh: clinical epidemiology and short-term outcomes in recovered individuals
Author(s) nameMannan A, Mehedi HMH, Chy NUHA, Qayum MO, Akter F, Rob MA, Biswas P, Hossain S, Ayub M.
Journal New Microbes New Infect
Impact factor1.6
Citation count1
Date of publishing2021 Mar
Household SARS-CoV-2 transmission (65) was the main source of 187 COVID-19 cases being reported, followed by unknown setting (45), imported cases (30) and workplace-related cases (39). An average number of 5.1 contacts were quarantined per each infected case, with 854 individuals totally being quarantined. 4 large transmission chains and 3 superspreading events were also reported.
PMID 33513332
Title Epidemiology and Clinical Course of First Wave Coronavirus Disease Cases, Faroe Islands
Author(s) nameKristiansen MF, Heimustovu BH, Borg S√Ā, Mohr TH, Gislason H, M√łller LF, Christiansen DH, Steig B√Ā, Petersen MS, Str√łm M, Gaini S.
Journal Emerg Infect Dis
Impact factor6.81
Citation count1
Date of publishing2021 Mar
Risk of prolonged COVID-19 infection was higher in individuals with higher BMI and triglycerides level, since BMI indirectly lowers IgG immune response when triglyceride levels are high. This is also owed to the direct impact of BMI and triglycerides on 7 proteins: CRP, Factor B and H, the interleukin 1 family of proteins, SAA/2, fibrinogen and antithrombin III via separate pathways.
PMID 33548839
Title Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2
Author(s) nameRichardson TG, Fang S, Mitchell RE, Holmes MV, Davey Smith G.
Journal EBioMedicine
Impact factor6.49
Citation count1
Date of publishing2021 Feb
Case fatality rate of 3.8% was reported in Karnataka with 54 deaths out of 1394 cases.
PMID 33521608
Title Descriptive epidemiology of SARS-CoV-2 infection in Karnataka state, South India: Transmission dynamics of symptomatic vs. asymptomatic infections
Author(s) nameKumar N, Shahul Hameed SK, Babu GR, Venkataswamy MM, Dinesh P, Kumar Bg P, John DA, Desai A, Ravi V.
Journal EClinicalMedicine
Impact factor6.68
Citation count1
Date of publishing2021 Feb
SARS-CoV-2 infections were transmitted mostly through: Travel (2264, 721%, including domestic (2136, 68%) and international (128, 4%) as well as known contact with a COVID-19 positive case (873, 278%). Overall SARS-CoV-2 test positivity rate was 1.1% in March and increased to 10% in May.
PMID 33521608
Title Descriptive epidemiology of SARS-CoV-2 infection in Karnataka state, South India: Transmission dynamics of symptomatic vs. asymptomatic infections
Author(s) nameKumar N, Shahul Hameed SK, Babu GR, Venkataswamy MM, Dinesh P, Kumar Bg P, John DA, Desai A, Ravi V.
Journal EClinicalMedicine
Impact factor6.68
Citation count1
Date of publishing2021 Feb
Higher risk of SARS-CoV-2 infections was observed in Delivery personnels, Informal traders (Salesman) and Transport sector workers compared to others. Overall COVID-19 Incidence rate was 41%.
PMID 33434668
Title Epidemiology of COVID-19 in Mexico: Symptomatic profiles andpresymptomatic people
Author(s) nameFernández-Rojas MA, Luna-Ruiz Esparza MA, Campos-Romero A, Calva-Espinosa DY, Moreno-Camacho JL, Langle-Martínez AP, García-Gil A, Solís-González CJ, Canizalez-Román A, León-Sicairos N, Alcántar-Fernández J.
Journal Int J Infect Dis
Impact factor3.42
Citation count1
Date of publishing2021 Jan 9
Mortality rate of COVID-19 patients in Northern Ireland was 17.7 per 100 000 population and generally lower than rest of the world.
PMID 33509318
Title Epidemiology of COVID-19 in Northern Ireland, 26 February 2020-26 April 2020
Author(s) namePett J, McAleavey P, McGurnaghan P, Spiers R, O'Doherty M, Patterson L, Johnston J.
Journal Epidemiol Infect
Impact factor2.01
Citation count1
Date of publishing2021 Jan 29
SARS-CoV-2 transmission was confirmed when 14 (31.8%) contacts out of 44 contacts tested positive for SARS-CoV-2, including 7 household and 6 high-risk contacts. Secondary attack rate was highest for household contacts (16%), compared to high-risk contacts (2.5%). Household contacts were reported to 11 times more likely to test positive for COVID-19 than high- or low-risk contacts.
PMID 33509318
Title Epidemiology of COVID-19 in Northern Ireland, 26 February 2020-26 April 2020
Author(s) namePett J, McAleavey P, McGurnaghan P, Spiers R, O'Doherty M, Patterson L, Johnston J.
Journal Epidemiol Infect
Impact factor2.01
Citation count1
Date of publishing2021 Jan 29
SARS-CoV-2 transmission via asymptomatic infections in infants was identified when a 14-day-old asymptomatic newborn was reported SARS-CoV-2 positive for PCR test, but no other newborns were tested positive at delivery. 52.6% of infants were admitted to NNU (Neonatal Unit) due to prematurity.
PMID 33521167
Title Epidemiology, management and risk of SARS-CoV-2 transmission in a cohort of newborns born to mothers diagnosed with COVID-19 infection
Author(s) nameSolís-García G, Gutiérrez-Vélez A, Pescador Chamorro I, Zamora-Flores E, Vigil-Vázquez S, Rodríguez-Corrales E, Sánchez-Luna M.
Journal An Pediatr (Engl Ed)
Impact factor1.3
Citation count1
Date of publishing2021 Jan 26
Risk of COVID-19 incidence decreased due to the implementation of lockdown measures and restricted movement. In addition, negative correlation was observed between temperature, relative humidity and COVID-19 transmission.
PMID 33495673
Title The Role of Weather Conditions in COVID-19 Transmission: A Study of a Global Panel of 1236 Regions
Author(s) nameZhang C, Liao H, Strobl E, Li H, Li R, Jensen SS, Zhang Y.
Journal J Clean Prod
Impact factor
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Date of publishing2021 Jan 16
Risk of COVID-19 transmission increased in nursing homes due to factors such as reduced staffing levels of total staff members and Licensed Practical Nurses (LPNs) as well as number of fines issued in 2020 because of non-conformity to the pandemic guidelines. Also, county-level factor like per-capita income (RR-1.86) showed a higher association with COVID-19 incidence in nursing homes compared to others.
PMID 32889290
Title Mapping community-level determinants of COVID-19 transmission in nursing homes: A multi-scale approach
Author(s) nameSugg MM, Spaulding TJ, Lane SJ, Runkle JD, Harden SR, Hege A, Iyer LS.
Journal Sci Total Environ
Impact factor5.9
Citation count4
Date of publishing2021 Jan 15
Transmisssion of SARS-CoV-2 via raw and treated wastewater was not considered as a mode of transmission conclusively due to absence of replicating viruses when grown in vitro, although RT-PCR results showed presence of virus in untreated and treated wastewater samples.
PMID 32861187
Title Detection of SARS-CoV-2 in raw and treated wastewater in Germany - Suitability for COVID-19 surveillance and potential transmission risks
Author(s) nameWesthaus S, Weber FA, Schiwy S, Linnemann V, Brinkmann M, Widera M, Greve C, Janke A, Hollert H, Wintgens T, Ciesek S.
Journal Sci Total Environ
Impact factor5.9
Citation count10
Date of publishing2021 Jan 10
Out of 10,449 Healthcare professionals, 136 showed seropositivity with 70% presenting with symptoms, including Cough (23.2%), Headache (22.1%) and Fatigue (21.1%).
PMID 33292895
Title Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) seroprevalence in healthcare personnel in northern California early in the coronavirus disease 2019 (COVID-19) pandemic
Author(s) nameRosser JI, Röltgen K, Dymock M, Shepard J, Martin A, Hogan CA, Blomkalns A, Mathew R, Parsonnet J, Pinsky BA, Maldonado YA, Boyd SD, Chang SI, Holubar M; Stanford Healthcare COVID-19 Workforce Response Group.
Journal Infect Control Hosp Epidemiol
Impact factor2.66
Citation count1
Date of publishing2020 Dec 9
Out of 30 COVID-19 patients, 23 showed the presence of anti-N antibodies, 20 showed anti-S** antibodies, and 13 had anti-M antibodies.
PMID 33330866
Title The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike
Author(s) nameGuo C, Tsai SJ, Ai Y, Li M, Pekosz A, Cox A, Atai N, Gould SJ.
Journal bioRxiv
Impact factorIts not a journal
Citation count1
Date of publishing2020 Dec 9
SARS-CoV-2 spread in Oman was contributed by the family clusters, out of 21 clusters which were reported.
PMID 33359061
Title Molecular epidemiology of COVID-19 in Oman: A molecular andsurveillance study for the early transmission of COVID-19 in thecountry
Author(s) nameAl-Mahruqi S, Al-Wahaibi A, Khan AL, Al-Jardani A, Asaf S, Alkindi H, Al-Kharusi S, Al-Rawahi AN, Al-Rawahi A, Al-Salmani M, Al-Shukri I, Al-Busaidi A, Al-Abri SS, Al-Harrasi A.
Journal Int J Infect Dis
Impact factor3.42
Citation count1
Date of publishing2020 Dec 21