Cytotoxicity


Select item(s)
Key Findings
Auranofin inhibited SARS-CoV-2 replication in Huh7 cells at CC50 5.7 micromolars.
PMID 32442105
Title The FDA-approved gold drug auranofin inhibits novel coronavirus (SARS-COV-2) replication and attenuates inflammation in human cells
Author(s) nameRothan HA, Stone S, Natekar J, Kumari P, Arora K, Kumar M.
Journal Virology
Impact factor2.819
Citation count20
Date of publishing2020 Aug
Cytotoxicity concentration of salinomycin sodium in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of lopinavir in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of remdesivir (GS-5734) in Vero cells was >25 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of tetrandrine in Vero cells was ~15 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of Triparanol in Vero cells was ~15 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Based on the cytopathic effect of the virus, chloroquine showed antiviral activity against SARS-CoV-2 at CC50 >37.5 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Based on the cytopathic effect of the virus, lopinavir showed antiviral activity against SARS-CoV-2 at CC50 >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Based on the cytopathic effect of the virus, remdesivir showed antiviral activity against SARS-CoV-2 at CC50 >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Based on the cytopathic effect of the virus, favipiravir showed antiviral activity against SARS-CoV-2 at CC50 >500 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Based on the cytopathic effect of the virus, atazanavir showed antiviral activity against SARS-CoV-2 at CC50 >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of toremifene citrate in Vero cells was ~10 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of proscillaridin in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of phenazopyridine hydrochloride in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of perhexiline maleate in Vero cells was ~9 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of penfluridol in Vero cells was ~9 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of oxyclozanide in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of ouabain in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of osimertinib mesylate in Vero cells was ~13 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of osajin in Vero cells was ~11 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of niclosamide in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of mequitazine in Vero cells was ~27 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of mefloquine in Vero cells was ~14 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of lusutrombopag in Vero cells was ~15 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23
Cytotoxicity concentration of abemaciclib in Vero cells was >50 micromolars.
PMID 32366720
Title Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs
Author(s) nameJeon S, Ko M, Lee J, Choi I, Byun SY, Park S, Shum D, Kim S.
Journal Antimicrob Agents Chemother
Impact factor4.68
Citation count119
Date of publishing2020 Jun 23