Conventional PCR assisted-nanodiagnosis assay


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Key Findings
A new nanotechnology-based PCR-assisted colorimetric SARS-CoV-2 detection assay works on the principle of 5'-exonuclease activity of polymerase and linker-based single-component assembly of gold nanoparticle-core spherical nucleic acids. The positive and negative viral samples produce red and purple colors in the post-PCR colorimetric test, respectively.
PMID 33012989
Title Conventional PCR Assisted Single-Component Assembly of Spherical Nucleic Acids for Simple Colorimetric Detection of SARS-CoV-2
Author(s) nameKarami A, Hasani M, Azizi Jalilian F, Ezati R.
Journal Sens Actuators B Chem
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Citation count2
Date of publishing2021 Feb 1